500 The Four Year Clinical and Economic Impact of an Extended Screening Program for Developmental Dysplasia of the Hip in Cardiff and Vale University Health Board

Abstract Aim Early detection of DDH is associated with the increased success non-surgical treatment. Therefore, Cardiff and Vale Health Board (CAVUHB) implemented an extended screening program for Developmental dysplasia Hip (DDH) to improve neonatal public health within population. Method A 4-year prospective case-control study all patients born between 01/01/2016-31/12/2019 (n = 21843) who underwent ultrasonographic in CAVUHB. Ultrasounds were graded using Graf’s classification, treatment outcomes determined by patient’s records costings based on NHS tariffs. Results Screening those risk factors diagnosed 49% treated cases. cost CAVUHB £175,000 per annum, a favourable outcome £12351. The mean late presenting patient was £23,782, incurring reduction 48%. Cost-effectiveness positive predictive value (PPV) calcaneovalgus malformations, oligohydramnios, plagiocephaly demonstrating PPV similar that primary factors. Calcaneovalgus malformations demonstrated significantly higher than (p < 0.05). Conclusions cost-effectively reduced morbidity surgical mortality population, as result its DDH. novel findings prevalence secondary marker treatable are significant, currently they not included national new-born infant physical examination (NIPE) guidance. High low population indicates these reducing clinically valuable markers disease could provide if program.